Quit Smoking Medications

Zyban (bupropion)

Back to Resources

This drug was first researched and marketed as an antidepressant, however bupropion was later found to be effective as a smoking cessation aid. It is believed to mimic the effects of nicotine on the brain and lessen your symptoms of withdrawal.

Consider using this product if you:

  • Feel that taking a medication would be the best option for you.
  • Prefer to not use a nicotine product.
  • Would like to use both a prescription medication along with a nicotine replacement product.

How it’s used:

  • Taken as a pill. Follow instructions as provided by your doctor or pharmacist.


  • The recommended and maximum dose of Zyban is 300 mg/day, given as 150 mg twice daily


  • Treatment should be continued for 7 to 12 weeks.

Watch out for:

  • May not be a good choice for people having a history of seizures, bulimia and/or anorexia, taking monoamine oxidase (MAO) inhibitors, or those who are allergic to bupropion hydrochloride.
  • Avoid use if you are alcohol dependent, taking St. John’s Wort and/or SSRI (selective reuptake inhibitor) antidepressants.
  • Common side effects include dry mouth and difficulty sleeping. These side effects are usually mild and temporary.
Powered by Giphy

Incoming Files